Your colleague keeps asking you for small favours even when she knows you have tons of work to do.
WHAT TO DO Make a list of what you have to do and all your deadlines, and show it to her. Tell her you can only help her out when your work is done. Ask if she can help you out, and look pleadingly into her eyes when doing so, says Agnes Lau, director of life-coaching consultancy, Mind Transformations.

Your colleague complains about everything, from her boss to her workload, even the canteen food!
WHAT TO DO “Take her aside and tell her in an empathetic tone that you understand her frustrations,” says Agnes. Express your concern by touching her hand lightly, and speaking to her in a caring tone. Then explain that you need to focus on your work and cannot give her constant attention. If she really needs someone to talk to, suggest discussing the matter over lunch or after work (if you’re willing to). Let her know it’s not personal, as work has to come first. The next time she complains, ignore her. If she bugs you, just say “not now”. And be firm.

A colleague who’s not your superior bosses you around and demands you do her work.
WHAT TO DO Look her in the eye and tell her, “I’m afraid I can’t. I have my own work to handle,” says Agnes. “Stand up to her in a nonconfrontational manner, assuming an unemotional tone of voice – unless you’d rather remain her doormat.”